PM&R
Volume 2, Issue 5 , Pages 384-392, May 2010

Fatigue in Systemic Lupus Erythematosus and Rheumatoid Arthritis

  • Rosalind Ramsey-Goldman, MD, DrPH

      Affiliations

    • Department of Medicine, 240 E. Huron, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611†
    • Corresponding Author InformationAddress correspondence to: R.R.-G.
    • ,
  • Nan Rothrock, PhD

      Affiliations

    • Department of Medical Social Sciences, Northwestern University Feinberg School of Medicine, Chicago, IL‡

Received 23 December 2009; accepted 21 March 2010.

Abstract

Two inflammatory autoimmune diseases, systemic lupus erythematosus and rheumatoid arthritis, are characterized by fatigue. Patient reports support the significant negative impact of the symptom on functioning and well-being. The prevalence, trajectory, mechanism, and correlates of fatigue in each disease are reviewed. Some disease-focused treatments have demonstrated a reduction in fatigue. However, until recently, clinical trials have not routinely assessed fatigue. Analyses and interpretation of data have been hindered by variability in the reliability and validity of fatigue measures. Empirically based fatigue treatment guidelines are needed in both conditions.

To access this article, please choose from the options below

Login to an existing account or Register a new account.

  • Purchase this article for 31.50 USD (You must login/register to purchase this article)

    Online access for 24 hours. The PDF version can be downloaded as your permanent record.

  • Subscribe to this title

    Get unlimited online access to this article and all other articles in this title 24/7 for one year.

  • Claim access now

    For current subscribers with Society Membership or Account Number.

  • Visit SciVerse ScienceDirect to see if you have access via your institution.
 
  • † Disclosure: nothing to disclose
  • ‡ Disclosure: 8B, NIH and NINDS

 Disclosure Key can be found on the Table of Contents and at www.pmrjournal.org

PII: S1934-1482(10)00294-7

doi:10.1016/j.pmrj.2010.03.026

PM&R
Volume 2, Issue 5 , Pages 384-392, May 2010

Article Tools