PM&R
Volume 2, Issue 4 , Pages 285-293 , April 2010

Performance-Enhancing Drugs

  • Jonathan T. Finnoff, DO (Guest Discussant)

      Affiliations

    • Department of Physical Medicine and Rehabilitation, Mayo Clinic, Rochester, MN⁎
    • Corresponding Author InformationAddress correspondence to: J.T.F.
    • ,
  • Gary P. Chimes, MD, PhD (Guest Discussant)

      Affiliations

    • UPMC, Pittsburgh, PA†
    • ,
  • Thomas H. Murray, PhD (Commentator)

      Affiliations

    • The Hastings Center, Garrison, NY‡

References 

    Jonathan T. Finnoff, DO, Responds
  1. World Anti-Doping Agency. Homepage. www.wada-ama.orgAccessed March 15, 2010
  2. Sjoqvist F, Garle M, Rane A. Use of doping agents, particularly anabolic steroids, in sports and society. Lancet. 2008;371:1872–1882
  3. United Nations Educational, Scientific and Cultural Organization. International Convention against Doping in Sport. http://portal.unesco.org/shs/en/ev.php-URL_ID=9682&URL_DO=DO_TOPIC&URL_SECTION=201.htmlAccessed March 15, 2010
  4. Larriviere D, Williams MA, Rizzo M, Bonnie RJ. Responding to requests from adult patients for neuroenhancements (Guidance of the ethics, law and humanities committee). Neurology. 2009;73:1–7
  5. Kanayama G, Hudson JI, Pope HG. Long-term psychiatric and medical consequences of AAS abuse: A looming public health concern?. Drug Alcohol Depend. 2008;98:1–12
    Gary P. Chimes, MD, PhD Responds
  1. Hoffman JR, Ratamess NA. Medical issues associated with anabolic steroid use: Are they exaggerated. J Sports Sci Med. 2006;5:182–193
  2. Bhasin S, Woodhouse L, Casaburi R, et al. Testosterone dose-response relationships in healthy young men. Am J Physiol Endocrinol Metab. 2001;281:E1172–E1181
  3. Bhasin S, Storer TW, Berman N, et al. The effects of supraphysiologic doses of testosterone on muscle size and strength in normal men. N Engl J Med. 1996;335:1–7
  4. Nindl BC, Barnes BR, Alemany JA. Physiologic consequences of U.S. Army Ranger training. Med Sci Sports Exerc. 2007;39:1380–1387
  5. Bouton J. Ball Four. New York: Collier Books; 1990;
  6. Kayser B, Smith AC. Globilisation of anti-doping: The reverse side of the medal. BMJ. 2008;337:a584
  7. Miller G. Neuropathology, a late hit for pro football players. Science. 2009;325:670–672
  8. McKee AC, Cantu RC, Nowinski CJ, et al. Chronic traumatic encephalopathy in athletes: Progressive tauopathy after repetitive head injury. J Neuropathol Exp Neurol. 2009;68:709–735
    Rebuttal from Dr. Finnoff
  1. Hoffman J, Ratamess NA. Medical issues associated with anabolic steroid use: Are they exaggerated?. J Sports Sci Med. 2006;5:182–193
  2. Kanayama G, Hudson JI, Pope HG. Long-term psychiatric and medical consequences of anabolic-androgenic steroid abuse: A looming public health concern?. Drug Alcohol Depend. 2008;98:1–12
  3. Parssinen M, Kujala U, Vartiainen E, Sarna S, Seppala T. Increased premature mortality of competitive powerlifters suspected to have used anabolic agents. Int J Sports Med. 2000;21:225–227
    Rebuttal from Dr Chimes
  1. Mirkin G. Review of Death in the Locker Room: Steroids and Sports. JAMA. 1984;252:2771
  2. Hoffman J, Ratamess NA. Medical issues associated with anabolic steroid use: Are they exaggerated?. J Sports Sci Med. 2006;5:182–193
  3. Hartgens F, Cheriex EC, Kuipers H. Prospective echocardiographic assessment of androgenic-anabolic steroids effects on cardiac structure and function in strength athletes. Int J Sports Med. 2003;24:344–351
  4. Alexander B. Good cop, bad cop (Outside Magazine). http://outside.away.com/outside/culture/201001/zach-lund-wada-1.htmlAccessed March 15, 2010
    Thomas H. Murray, PhD, Invited Commentary
  1. Sjöqvist F, Garle M, Rane A. Use of doping agents, particularly anabolic steroids, in sports and society. Lancet. 2008;371:1872–1882

PII: S1934-1482(10)00206-6

doi: 10.1016/j.pmrj.2010.03.016

PM&R
Volume 2, Issue 4 , Pages 285-293 , April 2010

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