PM&R
Volume 1, Issue 1 , Pages 60-63 , January 2009

Is Immediate Pain Relief After a Spinal Injection Procedure Enhanced by Intravenous Sedation?

  • Paul Dreyfuss, MD

      Affiliations

    • Department of Rehabilitation Medicine, University of Washington, 12301 NE 10th Place, Suite 101, Bellevue, WA 98004
    • Corresponding Author InformationAddress correspondence to: P.D.
  • ,
  • Steven Cohen, MD

      Affiliations

    • Department of Anesthesia and Critical Care Medicine, Johns Hopkins School of Medicine, Baltimore, Maryland, and Walter Reed Medical Center, Washington, DC
  • ,
  • Allen Sinclair Chen, MD, MPH

      Affiliations

    • Department of Rehabilitation Medicine, University of Washington, Seattle, WA
  • ,
  • Zach Bohart, MD, MS

      Affiliations

    • Department of Rehabilitation Medicine, University of Washington, Seattle, WA
  • ,
  • Nikolai Bogduk, MD, PhD, Dsc

      Affiliations

    • Department of Clinical Research, University of Newcastle, Royal Newcastle Hospital, New South Wales, Australia

Received 17 June 2008 ,Accepted 10 October 2008.

References 

  1. Ahmed SU, Tonidandel W, Trella J, Martin N, Chang Y. Peri-procedural protocols for interventional pain management techniques: A survey of US pain centers. Pain Phys. 2005;8:181–185
  2. Kim N, Delport E, Cucuzzella T, Marley J, Pruitt C. Is sedation indicated before spinal injections?. Spine. 2007;32:E748–E752
  3. Valat JP, Giraudeau B, Rozenberg S, et al. Epidural corticosteroid injections for sciatica: A randomised, double-blind, controlled clinical trial. Ann Rheum Dis. 2003;62:639–643
  4. Johansson A, Hao J, Sjolund B. Local corticosteroid application blocks transmission in normal nociceptive C-fibres. Acta Anaesthesiol Scand. 1990;34:335–338
  5. Johansson A, Bennett GJ. Effect of local methylprednisolone on pain in a nerve injury model. Regional Anesthesia. 1997;22:59–65
  6. Takeda K, Sawamura S, Sekiyama H, Tamai H, Hanaoka K. Effect of methylprednisolone on neuropathic pain and spinal glial activation in rats. Anesthesiology. 2004;100:1249–1257
  7. Beecher HK. The powerful placebo. JAMA. 1955;159:1602–1606
  8. Thompson WG. Placebos: A review of the placebo response. Am J Gastroenterol. 2000;95:1637–1643
  9. Jenson M, Karoly P. Motivation and expectancy factors in symptom perception: A laboratory study of the placebo effect. Psychosomatic Med. 1991;53:144–152
  10. Price DD, Milling LS, Kirsch I, Duff A, Montgomery GH, Nicholls SS. An analysis of factors that contribute to the magnitude of placebo analgesia in an experimental paradigm. Pain. 1999;83:147–156
  11. De Pascalis V, Chiaradia C, Carotenuto E. The contribution of suggestibility and expectation to placebo analgesia phenomenon in an experimental setting. Pain. 2002;96:393–402
  12. Kaptchuk T, Goldman P, Stone D, Stason W. Do medical devices have enhanced placebo effects?. J Clin Epidemiol. 2000;53:786–792

 Disclosure Key can be found on the Table of Contents and at www.pmrjournal.org

PII: S1934-1482(08)00013-0

doi: 10.1016/j.pmrj.2008.10.006

PM&R
Volume 1, Issue 1 , Pages 60-63 , January 2009